DEP-Dots for 3D cell culture

pharmacodane

DEP-Dots for 3D cell culture: low-cost, high-repeatability, effective 3D cell culture in multiple gel systems

It is known that cells grown in 3D are more tolerant to drug treatment than those grown in dispersion, but the mechanism for this is still not clear; cells grown in 3D have opportunities to develop inter-cell communication, but are also closely packed which may impede diffusion.
In this study we examine methods for dielectrophoresis-based cell aggregation of both suspension and adherent cell lines, and compare the effect of various drugs on cells grown in 3D and 2D. Comparing viability of pharmacological interventions on 3D cell clusters against both suspension cells and adherent cells grown in monolayer, as well as against a unicellular organism with no propensity for intracellular communication, we suggest that 3D aggregates of adherent cells, compared to suspension cells, show a substantially different drug response to cells grown in monolayer, which increases as the IC50 is approached.
Further, a mathematical model of the system for each agent demonstrates that changes to drug response are due to inherent changes in the system of adherent cells from the 2D to 3D state. Finally, differences in the electrophysiological membrane properties of the adherent cell type suggest this parameter plays an important role in the differences found in the 3D drug response.
pharmacodane

pharmacodane

rHu MIP-3-beta

AK8232-0100 100µg Ask for price

rHu MIP-3-beta

AK8232-1000 1mg Ask for price

rHu MIP-1-beta

AK8264-0002 2µg Ask for price

rHu MIP-1-beta

AK8264-0010 10µg Ask for price

rHu MIP-1-beta

AK8264-0100 100µg Ask for price

rHu MIP-1-beta

AK8264-1000 1mg Ask for price

rHu MIP-1-alpha

AK8250-0005 5µg Ask for price

rHu MIP-1-alpha

AK8250-0020 20µg Ask for price

rHu MIP-1-alpha

AK8250-0100 100µg Ask for price

rHu MIP-1-alpha

AK8250-1000 1mg Ask for price

rHu MIP-3-alpha

AK8271-0005 5µg Ask for price

rHu MIP-3-alpha

AK8271-0020 20µg Ask for price

rHu MIP-3-alpha

AK8271-0100 100µg Ask for price

rHu MIP-3-alpha

AK8271-1000 1mg Ask for price

rHu IL-4

AK8329-0005 5µg Ask for price

rHu IL-4

AK8329-0020 20µg Ask for price

rHu IL-4

AK8329-0100 100µg Ask for price

rHu IL-4

AK8329-1000 1mg Ask for price

rHu MCP-4

AK8332-0005 5µg Ask for price

rHu MCP-4

AK8332-0020 20µg Ask for price

rHu MCP-4

AK8332-0100 100µg Ask for price

rHu MCP-4

AK8332-1000 1mg Ask for price

rHu FGF-4

AK9698-0005 5µg Ask for price

rHu FGF-4

AK9698-0025 25µg Ask for price

rHu FGF-4

AK9698-0100 100µg Ask for price

rHu FGF-4

AK9698-1000 1mg Ask for price

rHu IL-4 (cGMP)

AK9839-0000 1mg Ask for price

rHu BMP-4 (CHO)

AK9996-0005 5µg Ask for price

rHu BMP-4 (CHO)

AK9996-0020 20µg Ask for price

rHu BMP-4 (CHO)

AK9996-0100 100µg Ask for price

rHu BMP-4 (CHO)

AK9996-1000 1mg Ask for price

MIP-4

GWB-915E16 0.01 mg Ask for price

MIP 4

chm-322 2µg
EUR 60
Description: Recombinant Human Macrophage Inflammatory protein-4 (CCL18)

rHu MIF

AK8255-0005 5µg Ask for price

rHu MIF

AK8255-0025 25µg Ask for price

rHu MIF

AK8255-0100 100µg Ask for price

rHu MIF

AK8255-1000 1mg Ask for price

rHu EGF

AK8327-0100 100µg Ask for price

rHu EGF

AK8327-0500 500µg Ask for price

rHu EGF

AK8327-1000 1mg Ask for price

rHu OSM

AK8531-0002 2µg Ask for price

rHu OSM

AK8531-0010 10µg Ask for price

rHu OSM

AK8531-0100 100µg Ask for price

rHu OSM

AK8531-1000 1mg Ask for price

rHu SHH

AK9088-0005 5µg Ask for price

rHu SHH

AK9088-0025 25µg Ask for price

rHu SHH

AK9088-0100 100µg Ask for price

rHu SHH

AK9088-1000 1mg Ask for price

rHu TPO

AK9089-0002 5µg Ask for price

rHu TPO

AK9089-0010 20µg Ask for price

rHu TPO

AK9089-0100 100µg Ask for price

rHu TPO

AK9089-1000 1mg Ask for price

rHu PTN

AK9912-0005 5µg Ask for price

rHu PTN

AK9912-0020 20µg Ask for price

rHu PTN

AK9912-0100 100µg Ask for price

rHu PTN

AK9912-1000 1mg Ask for price

rHu LIF

AK9977-0005 5µg Ask for price

rHu LIF

AK9977-0025 25µg Ask for price

rHu LIF

AK9977-0100 100µg Ask for price

rHu LIF

AK9977-1000 1mg Ask for price

rHu MIG

AK9979-0005 5µg Ask for price

rHu MIG

AK9979-0020 20µg Ask for price

rHu MIG

AK9979-0100 100µg Ask for price

rHu MIG

AK9979-1000 1mg Ask for price

rHu aFGF

AK8230-0010 10µg Ask for price

rHu aFGF

AK8230-0050 50µg Ask for price

rHu aFGF

AK8230-0100 100µg Ask for price

rHu aFGF

AK8230-1000 1mg Ask for price

rHu MCSF

AK8238-0002 2µg Ask for price

rHu MCSF

AK8238-0010 10µg Ask for price

rHu MCSF

AK8238-0100 100µg Ask for price

rHu MCSF

AK8238-1000 1mg Ask for price

rHu CTGF

AK8240-0005 5µg Ask for price

rHu CTGF

AK8240-0020 20µg Ask for price

rHu CTGF

AK8240-0100 100µg Ask for price

rHu CTGF

AK8240-1000 1mg Ask for price

rHu BDNF

AK8286-0002 2µg Ask for price

rHu BDNF

AK8286-0010 10µg Ask for price

rHu BDNF

AK8286-0100 100µg Ask for price

rHu BDNF

AK8286-1000 1mg Ask for price

rHu CNTF

AK8302-0005 5µg Ask for price

rHu CNTF

AK8302-0020 20µg Ask for price

rHu CNTF

AK8302-0100 100µg Ask for price

rHu CNTF

AK8302-1000 1mg Ask for price

rHu GDNF

AK8335-0002 2µg Ask for price

rHu GDNF

AK8335-0010 10µg Ask for price

rHu GDNF

AK8335-0100 100µg Ask for price

rHu GDNF

AK8335-1000 1mg Ask for price

rHu BAFF

AK8540-0005 5µg Ask for price

rHu BAFF

AK8540-0020 20µg Ask for price

rHu BAFF

AK8540-0100 100µg Ask for price

rHu BAFF

AK8540-1000 1mg Ask for price

rHu TSLP

AK9091-0002 2µg Ask for price

rHu TSLP

AK9091-0010 10µg Ask for price

rHu TSLP

AK9091-0100 100µg Ask for price

rHu TSLP

AK9091-1000 1mg Ask for price

rHu TRAIL

AK9090-0010 10µg Ask for price

rHu TRAIL

AK9090-0050 50µg Ask for price

rHu TRAIL

AK9090-0100 100µg Ask for price

Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults

Humanin (HN) is a 24-amino acid mitochondrial-derived peptide, best known for its ability to protect neurons from damage caused by ischemic stroke and neurodegenerative insults and cardiomyocytes from myocardial infarction or doxorubicin (Dox)-induced cardiotoxicity.
This study examines the neuroprotective and myoprotective effects of HN novel synthetic analogs HUJInin and c(d-ser14)HN, prepared by solid-phase peptide synthesis. The cellular models employed were oxygen-glucose-deprivation (OGD) followed by reoxygenation (R)-induced neurotoxicity in PC12 and SH-SY5Y neuronal cell cultures and Dox-induced cardiotoxicity in H9c2 and C2C12 myoblast cell cultures, respectively.
Necrotic and apoptotic cell death was measured by LDH release and caspase-3 activity. Erk 1/2 and AKT phosphorylations were examined by western blotting. Mitochondrial calcium and mitochondrial membrane potential were measured using the fluorescent dye tetramethylrhodamine-methyl ester. It was found that HUJInin and c(d-ser14)HN conferred significant dose-dependent neuroprotection, a phenomenon related to attenuation of OGD insult-induced Erk 1/2 phosphorylation, stimulation of AKT phosphorylation and improvement of mitochondrial functions.
These peptides also conferred myoprotective effect towards (Dox)-induced apo-necrotic cell death insults. HUJInin and c(d-ser14)HN synthetic analogs may provide new lead compounds for the development of a potential candidate drug for stroke treatment and/or DOX-induced cardiotoxicity therapy in cancer patients.

Enhancing the Furosemide Permeability by Papain Minitablets Through a Triple Co-culture In Vitro Intestinal Cell Model

The administration of medicines by the oral route is the most used approach for being very convenient. Although it is the most popular, this route also has absorption, and consequently, bioavailability limitations. In this sense, several pharmacotechnical strategies have been used to improve drug absorption, one of which is the use of permeation promoters.
Papain is a very versatile plant enzyme that can be used as a permeation promoter of various active compounds. This study aimed to evaluate the safety of papain and the formulation of native papain minitablets to promote in vitro permeation of furosemide through an innovative biomimetic triple co-culture model of Caco-2, HT29-MTX, and Raji cells.
Regarding permeation, furosemide and metaprolol concentrations are determined with HPLC; those are used to calculate Papp. Monolayer integrity was evaluated using TEER and Lucifer Yellow. In the presence of papain, TEER decreased two-fold and the Papp of furosemide increased six-fold.
The results suggest that native papain minitablets can be used as therapeutic adjuvants to enhance the permeation of drugs significantly improving bioavailability.

Recombinant Human MIP-3 beta

MBS7611183-005mg 0.05mg
EUR 345

Recombinant Human MIP-3 beta

MBS7611183-02mg 0.2mg
EUR 635

Recombinant Human MIP-3 beta

MBS7611183-1mg 1mg
EUR 1800

Recombinant Human MIP-3 beta

MBS7611183-5x1mg 5x1mg
EUR 6955

Recombinant Mouse MIP-3 beta

MBS7608911-005mg 0.05mg
EUR 345

Recombinant Mouse MIP-3 beta

MBS7608911-02mg 0.2mg
EUR 635

Recombinant Mouse MIP-3 beta

MBS7608911-1mg 1mg
EUR 1800

Recombinant Mouse MIP-3 beta

MBS7608911-5x1mg 5x1mg
EUR 6955

Recombinant CCL19 (MIP-3β)

MBS197063-0005mg 0.005mg
EUR 175

Recombinant CCL19 (MIP-3β)

MBS197063-002mg 0.02mg
EUR 285

Recombinant CCL19 (MIP-3β)

MBS197063-005mg 0.05mg
EUR 405

Recombinant CCL19 (MIP-3β)

MBS197063-01mg 0.1mg
EUR 605

Recombinant CCL19 (MIP-3β)

MBS197063-1mg 1mg
EUR 2540

MIP-3 beta Recombinant Protein

40-354-0005mg 0.005 mg
EUR 311.1
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant murine MIP-3 beta is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 beta Recombinant Protein

40-354-002mg 0.02 mg
EUR 437.1
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant murine MIP-3 beta is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 beta Recombinant Protein

40-381-0005mg 0.005 mg
EUR 311.1
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 beta Recombinant Protein

40-381-002mg 0.02 mg
EUR 437.1
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Human MIP-3 beta ELISA Kit

GWB-SKR155 96 Tests Ask for price

RABBIT ANTI HUMAN MIP-3 BETA

MBS221727-01mg 0.1mg
EUR 635

RABBIT ANTI HUMAN MIP-3 BETA

MBS221727-5x01mg 5x0.1mg
EUR 2695

MIP-3 beta, CCL19, murine (mouse)

RC335-20 5ug
EUR 121.6

Anti-Human MIP-3 beta Antibody

101-M80 500 µg
EUR 246.75
Description: MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Anti-Human MIP-3 beta Antibody

102-P68 100 µg
EUR 245.7
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on mouse cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Human MIP-3 beta (CCL19)

Z101945 20 µg
EUR 195
Description: CCL19 is a chemokine that belongs to the CC family of growth factors and signals through the CCR7 receptor. CCl19 has been shown to be expressed in the thymus, lymph nodes and in activated bone marrow stromal cells. When anti-inflammatory signals are released, expression of CCL19 gets down-regulated – specifically by IL-10.

Recombinant Human MIP-3 beta (CCL19)

Z101949 1.0 mg
EUR 3900
Description: CCL19 is a chemokine that belongs to the CC family of growth factors and signals through the CCR7 receptor. CCl19 has been shown to be expressed in the thymus, lymph nodes and in activated bone marrow stromal cells. When anti-inflammatory signals are released, expression of CCL19 gets down-regulated – specifically by IL-10.

Recombinant Human MIP-3 beta (CCL19)

MBS4159807-002mg 0.02mg
EUR 345

Recombinant Human MIP-3 beta (CCL19)

MBS4159807-1mg 1(mg)
EUR 4600

Recombinant Human MIP-3 beta (CCL19)

MBS4159807-5x1mg 5x1mg
EUR 20445

Recombinant Murine MIP-3 beta /CCL19

MECCP-1901 5ug Ask for price

Human CCL19/MIP-3 Beta ELISA Kit

EK5194 96 tests
EUR 599

Mouse CCL19/MIP-3 beta ELISA Kit

EK5195 96 tests
EUR 599

Human CCL19/MIP-3 beta ELISA Kit

LF-EK50840 1×96T
EUR 777.6

CCL19 / MIP-3 beta (Human) ELISA Kit

EK-045-68 96 wells
EUR 603.72

Rat MIP-1 beta

MBS691673-0005mg 0.005mg
EUR 300

Rat MIP-1 beta

MBS691673-002mg 0.02mg
EUR 450

Rat MIP-1 beta

MBS691673-5x002mg 5x0.02mg
EUR 1725

Mouse MIP-1 beta

MBS691963-0002mg 0.002mg
EUR 300

Mouse MIP-1 beta

MBS691963-001mg 0.01mg
EUR 450

Mouse MIP-1 beta

MBS691963-5x001mg 5x0.01mg
EUR 1725

MIP-1 beta Antibody

GWB-185AB9 0.1 mg Ask for price

MIP-1 beta Antibody

R30450 100 ug
EUR 356.15
Description: Chemokine(C-C motif) ligand 4, also known as CCL4 and MIP-1 beta, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. MIP-1 beta is a major HIV-suppressive factor produced by CD8+ T cells.

Anti-Ccl19/MIP-3 beta Picoband Antibody

MBS1750677-01mg 0.1mg
EUR 450

Anti-Ccl19/MIP-3 beta Picoband Antibody

MBS1750677-5x01mg 5x0.1mg
EUR 1870

MIP 1 beta antibody

20R-1789 100 ug
EUR 807.6
Description: Rabbit polyclonal MIP 1 beta antibody

MIP 1 beta antibody

MBS835136-INQUIRE INQUIRE Ask for price

Human MIP-3 beta (CCL19) Recombinant Protein

100-079 20 µg
EUR 196.35
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Human MIP-3 beta (CCL19) Recombinant Protein

100-079S 5 µg
EUR 92.4
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Human MIP-3 Beta (CCL19) Protein

PROTQ99731-1 20ug
EUR 380.4
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Mouse MIP-3 beta (CCL19) Recombinant Protein

M10-079 20 µg
EUR 196.35
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Mouse urine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Mouse MIP-3 beta (CCL19) Recombinant Protein

M10-079S 5 µg
EUR 92.4
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Mouse urine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Human CCL19/MIP-3 beta Protein

RP01634 100μg
EUR 39

Recombinant Mouse MIP-3 Beta/CCL19 protein

CD00293-5ug 5ug
EUR 176
Description: CCL19, also known as EBI1 Ligands chemokine (ELC) and macrophage inflammatory protein-3-beta, is encoded by the CCL19 gene which is located on chromosome 4 in mouse. The protein is expressed at high levels in thymus and lymph nodes, with intermediate levels in trachea and colon and low levels in stomach, lung and some other organs. CCL19 is signal through CCR7 and chemotaxis of T and B lymphocytes and myeloid progenitor cells.

Recombinant Human CCL19/MIP-3 beta Protein

RP01832 10μg
EUR 364.88

Recombinant Murine MIP-3 Beta (CCL19) Protein

PROTO70460-2 20ug
EUR 380.4
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

OPSD00071-5UG - Recombinant MIP-3 beta / CCL19

OPSD00071-5UG 5ug
EUR 108

OPSD00132-5UG - Recombinant MIP-3 beta / CCL19

OPSD00132-5UG 5ug
EUR 108

Human MIP-3 beta Recombinant Protein Lyophilized

IHUMIP3BRLY5UG each
EUR 341
Description: Human MIP-3 beta Recombinant Protein Lyophilized

Mouse MIP-3 beta Recombinant Protein Lyophilized

IMSMIP3BRLY5UG each
EUR 341
Description: Mouse MIP-3 beta Recombinant Protein Lyophilized

Human MIP-3 beta Recombinant Protein Lyophilized

MBS8432772-INQUIRE INQUIRE Ask for price

Mouse MIP-3 beta Recombinant Protein Lyophilized

MBS8434280-INQUIRE INQUIRE Ask for price

Mouse Anti-Human MIP-3 alpha (beta)

MBS690310-05mg 0.5mg
EUR 525

Mouse Anti-Human MIP-3 alpha (beta)

MBS690310-5x05mg 5x0.5mg
EUR 2080

Human CCL19/MIP-3 beta PicoKine ELISA Kit

EK0456 96 wells
EUR 510
Description: For quantitative detection of human CCL19 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse CCL19/MIP-3 beta PicoKine ELISA Kit

EK0457 96 wells
EUR 510
Description: For quantitative detection of mouse CCL19 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CCL19/MIP-3 beta PicoKine ELISA Kit

MBS176518-5x96StripWells 5x96-Strip-Wells
EUR 2755

Human CCL19/MIP-3 beta PicoKine ELISA Kit

MBS176518-96StripWells 96-Strip-Wells
EUR 600

Mouse CCL19/MIP-3 beta PicoKine ELISA Kit

MBS177585-5x96StripWells 5x96-Strip-Wells
EUR 2755

Mouse CCL19/MIP-3 beta PicoKine ELISA Kit

MBS177585-96StripWells 96-Strip-Wells
EUR 600

MIP-1 beta, CCL4, rat

RC355-15 5ug
EUR 125.26

OKRC00720-96W - MIP-3 beta ELISA Kit (Human)

OKRC00720-96W 96Wells
EUR 525

OKRC01262-96W - MIP-3 beta ELISA Kit (Mouse)

OKRC01262-96W 96Wells
EUR 525

MIP-1 beta, CCL4, human

RC314-15 2ug
EUR 121.6

Human MIP-1 beta (CCL4)

MBS692135-0002mg 0.002mg
EUR 300

Human MIP-1 beta (CCL4)

MBS692135-001mg 0.01mg
EUR 450

Human MIP-1 beta (CCL4)

MBS692135-5x001mg 5x0.01mg
EUR 1725

CCL4 Antibody / MIP-1 beta

R31955 100 ug
EUR 356.15
Description: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. And it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).

Rabbit Anti Human Mip-3 Beta Polyclonal Antibody

CPBT-65218RH 0.1 mg
EUR 1057.2

Recombinant Pig MIP-1 Beta

MBS225413-0005mg 0.005mg
EUR 355

Recombinant Pig MIP-1 Beta

MBS225413-5x0005mg 5x0.005mg
EUR 1435

Human recombinant MIP-1 beta

MI-300-3 10ug
EUR 200

Human recombinant MIP-1 beta

MI-300-4 50ug
EUR 800

Human recombinant MIP-2 beta

MI-320-3 10ug
EUR 200

Human recombinant MIP-2 beta

MI-320-4 50ug
EUR 800

rHu MIP-3-beta

AK8232-0005 5µg Ask for price

rHu MIP-3-beta

AK8232-0020 20µg Ask for price

rHu MIP-3-beta

AK8232-0100 100µg Ask for price

rHu MIP-3-beta

AK8232-1000 1mg Ask for price

MIP-1 beta Recombinant Protein

40-358-0002mg 0.002 mg
EUR 311.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein

40-358-001mg 0.01 mg
EUR 437.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein

40-365-0002mg 0.002 mg
EUR 311.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein

40-365-001mg 0.01 mg
EUR 437.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein

40-407-0005mg 0.005 mg
EUR 311.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein

40-407-002mg 0.02 mg
EUR 437.1
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3-beta Antibody

abx235194-100ug 100 ug
EUR 577.2

MIP-3-beta Antibody

abx235194-100g 100 µg
EUR 350

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody

M01605 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal CCL19/Mip 3 Beta Antibody. Validated in WB and tested in Human.

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody

MBS179703-01mL 0.1mL
EUR 450

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody

MBS179703-5x01mL 5x0.1mL
EUR 1870

CXCL2 (Gro beta, MIP-2)

MBS614445-01mg 0.1mg
EUR 840

CXCL2 (Gro beta, MIP-2)

MBS614445-5x01mg 5x0.1mg
EUR 3625

Human MIP-3 Beta Flow Cytometry Assay - Group 6

HX87223 96 Tests
EUR 270

Rat Monoclonal anti-mouse CCL-19 (MIP-3 beta)

mAP-0171 100ug
EUR 250

Mouse Monoclonal anti-human CCL-19 (MIP-3 beta)

hAP-0143 100ug
EUR 250

Sheep Polyclonal anti-Human CCL-19 (MIP-3 beta)

hAP-5710 50ug
EUR 400

Mouse MIP-1 beta ELISA Kit

GWB-SKR096 96 Tests Ask for price

MIP-1 beta (human) ELISA Kit

K4785-100 100 assays
EUR 970.8
Description: Sensitive, Colorimetric Assay

Rabbit anti Pig MIP-1 Beta

MBS225020-01mg 0.1mg
EUR 645

Rabbit anti Pig MIP-1 Beta

MBS225020-5x01mg 5x0.1mg
EUR 2730

Rabbit anti Pig MIP-1 Beta

MBS225021-005mg 0.05mg
EUR 645

Rabbit anti Pig MIP-1 Beta

MBS225021-5x005mg 5x0.05mg
EUR 2730

Pig MIP-1 Beta (CCL4) Protein

abx670310-5ug 5 ug
EUR 493.2

Pig MIP-1 Beta (CCL4) Protein

abx670310-100g 100 µg
EUR 312.5

MIP-1 beta, CCL4, murine (mouse)

RC335-15 2ug
EUR 125.26

RABBIT ANTI HUMAN MIP-1 BETA

MBS221343-01mg 0.1mg
EUR 635

RABBIT ANTI HUMAN MIP-1 BETA

MBS221343-5x01mg 5x0.1mg
EUR 2695

Rabbit Anti Human Mip-3 Beta Polyclonal Antibody,Biotin

CPBT-65217RH 50 µg
EUR 1057.2

MIP-1 beta Rabbit mAb, capture

E2RB20113UC 100ul
EUR 485
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Anti-Human MIP-1 beta Antibody

102-P64 100 µg
EUR 245.7
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant human MIP-1βis a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines

Anti-Mouse MIP-1 beta Antibody

103-P79 100 µg
EUR 245.7
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant murine MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Human MIP-1 beta/CCL4

HECCP-0401 10ug Ask for price

Human MIP-1 beta (CCL4) Recombinant

MBS553044-0002mg 0.002mg
EUR 165

Human MIP-1 beta (CCL4) Recombinant

MBS553044-001mg 0.01mg
EUR 245

CXCL2 (Gro beta, MIP-2) (AP)

MBS6470975-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (AP)

MBS6470975-5x01mL 5x0.1mL
EUR 4875

CXCL2 (Gro beta, MIP-2) (PE)

MBS6470996-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (PE)

MBS6470996-5x01mL 5x0.1mL
EUR 4875

Rat MIP-1 beta Recombinant Protein

R20-035 20 µg
EUR 196.35
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant rat MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Rat MIP-1 beta Recombinant Protein

R20-035S 5 µg
EUR 92.4
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant rat MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Human MIP-1 beta (CCL4L1)

Z102105 10 µg
EUR 85
Description: MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.

Recombinant Human MIP-1 beta (CCL4L1)

Z102107 100 µg
EUR 600
Description: MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.

Recombinant Human MIP-1 beta (CCL4L1)

Z102109 1.0 mg
EUR 3250
Description: MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.

Recombinant Human MIP-1 beta (CCL4L1)

MBS4159822-001mg 0.01mg
EUR 230

Recombinant Human MIP-1 beta (CCL4L1)

MBS4159822-01mg 0.1mg
EUR 810

Recombinant Human MIP-1 beta (CCL4L1)

MBS4159822-1mg 1mg
EUR 3850

Recombinant Human MIP-1 beta (CCL4L1)

MBS4159822-5x1mg 5x1mg
EUR 17080

CXCL2 (Gro beta, MIP-2) (APC)

MBS6470976-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (APC)

MBS6470976-5x01mL 5x0.1mL
EUR 4875

CXCL2 (Gro beta, MIP-2) (HRP)

MBS6470990-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (HRP)

MBS6470990-5x01mL 5x0.1mL
EUR 4875

Human MIP-1 beta Recombinant Protein

100-074 10 µg
EUR 196.35
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant human MIP-1βis a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Human MIP-1 beta Recombinant Protein

100-074S 2 µg
EUR 92.4
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant human MIP-1βis a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Mouse MIP-1 beta Recombinant Protein

M10-077 10 µg
EUR 196.35
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant murine MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Mouse MIP-1 beta Recombinant Protein

M10-077S 2 µg
EUR 92.4
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant murine MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

CXCL2 (Gro beta, MIP-2) (FITC)

MBS6470978-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (FITC)

MBS6470978-5x01mL 5x0.1mL
EUR 4875

Rabbit polyclonal MIP-1 beta antibody

TA319165 100 µg Ask for price

Rat GRO Beta/Mip-2 Antibody

GWB-2FD7C5 0.1 mg Ask for price

CXCL2 (Gro beta, MIP-2) (Biotin)

MBS6470977-01mL 0.1mL
EUR 1115

CXCL2 (Gro beta, MIP-2) (Biotin)

MBS6470977-5x01mL 5x0.1mL
EUR 4875

GRO beta / MIP-2 (CXCL2) Protein

20-abx261572
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 ug
  • 1 mg
  • 2 µg

GRO beta / MIP-2 (CXCL2) Protein

20-abx261590
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

GRO beta / MIP-2 (CXCL2) Protein

20-abx261604
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

Human MIP-1 Beta (CCL4) Flow Cytometry Assay - Group 3

HX88521 96 Tests
EUR 210

Mouse MIP-3 Beta (CCL19) Flow Cytometry Assay - Group 4

MX30222 96 Tests
EUR 270

Human CCL19 / MIP-3 beta Protein, Tag Free (HPLC verified)

CC9-H5215 50ug
EUR 3092.3
Description: Human CCL19, Tag Free (CC9-H5215) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ser 98 (Accession # Q99731-1).

MIP-3-beta/CCL19, Mouse

HY-P7264 50ug
EUR 639.6

anti- MIP-3-beta antibody

FNab05194 100µg
EUR 606.3
Description: Antibody raised against MIP-3-beta

Recombinant Human MIP-3 beta/ CCL19 Protein, GST, E.coli-1mg

QP8024-ec-1mg 1mg
EUR 1958.4

Rat CCL4/MIP-1 Beta ELISA Kit

EK5423 96 tests
EUR 599

Rat CCL4/MIP-1 beta ELISA Kit

LF-EK50964 1×96T
EUR 777.6

Recombinant Human MIP-3 beta/ CCL19 Protein, GST, E.coli-10ug

QP8024-ec-10ug 10ug
EUR 240

Recombinant Human MIP-3 beta/ CCL19 Protein, GST, E.coli-50ug

QP8024-ec-50ug 50ug
EUR 315.6

Recombinant Human MIP-3 beta/ CCL19 Protein, GST, E.coli-100ug

QP8024-ec-100ug 100ug
EUR 489.6

Skriv et svar

Din e-mailadresse vil ikke blive publiceret.