DEP-Dots for 3D cell culture

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pharmacodane

DEP-Dots for 3D cell culture: low-cost, high-repeatability, effective 3D cell culture in multiple gel systems

It is known that cells grown in 3D are more tolerant to drug treatment than those grown in dispersion, but the mechanism for this is still not clear; cells grown in 3D have opportunities to develop inter-cell communication, but are also closely packed which may impede diffusion.
In this study we examine methods for dielectrophoresis-based cell aggregation of both suspension and adherent cell lines, and compare the effect of various drugs on cells grown in 3D and 2D. Comparing viability of pharmacological interventions on 3D cell clusters against both suspension cells and adherent cells grown in monolayer, as well as against a unicellular organism with no propensity for intracellular communication, we suggest that 3D aggregates of adherent cells, compared to suspension cells, show a substantially different drug response to cells grown in monolayer, which increases as the IC50 is approached.
Further, a mathematical model of the system for each agent demonstrates that changes to drug response are due to inherent changes in the system of adherent cells from the 2D to 3D state. Finally, differences in the electrophysiological membrane properties of the adherent cell type suggest this parameter plays an important role in the differences found in the 3D drug response.
pharmacodane

pharmacodane

rHu MIP-3-beta
AK8232-0100 100µg Ask for price

rHu MIP-3-beta
AK8232-1000 1mg Ask for price

rHu MIP-1-alpha
AK8250-0005 5µg Ask for price

rHu MIP-1-alpha
AK8250-0020 20µg Ask for price

rHu MIP-1-alpha
AK8250-0100 100µg Ask for price

rHu MIP-1-alpha
AK8250-1000 1mg Ask for price

rHu MIP-1-beta
AK8264-0002 2µg Ask for price

rHu MIP-1-beta
AK8264-0010 10µg Ask for price

rHu MIP-1-beta
AK8264-0100 100µg Ask for price

rHu MIP-1-beta
AK8264-1000 1mg Ask for price

rHu MIP-3-alpha
AK8271-0005 5µg Ask for price

rHu MIP-3-alpha
AK8271-0020 20µg Ask for price

rHu MIP-3-alpha
AK8271-0100 100µg Ask for price

rHu MIP-3-alpha
AK8271-1000 1mg Ask for price

rHu IL-4
AK8329-0005 5µg Ask for price

rHu IL-4
AK8329-0020 20µg Ask for price

rHu IL-4
AK8329-0100 100µg Ask for price

rHu IL-4
AK8329-1000 1mg Ask for price

rHu MCP-4
AK8332-0005 5µg Ask for price

rHu MCP-4
AK8332-0020 20µg Ask for price

rHu MCP-4
AK8332-0100 100µg Ask for price

rHu MCP-4
AK8332-1000 1mg Ask for price

rHu FGF-4
AK9698-0005 5µg Ask for price

rHu FGF-4
AK9698-0025 25µg Ask for price

rHu FGF-4
AK9698-0100 100µg Ask for price

rHu FGF-4
AK9698-1000 1mg Ask for price

rHu IL-4 (cGMP)
AK9839-0000 1mg Ask for price

rHu IL-4 (cGMP)
AK9839-0100 100ug Ask for price

rHu BMP-4 (CHO)
AK9996-0005 5µg Ask for price

rHu BMP-4 (CHO)
AK9996-0020 20µg Ask for price

rHu BMP-4 (CHO)
AK9996-0100 100µg Ask for price

rHu BMP-4 (CHO)
AK9996-1000 1mg Ask for price

MIP-4/CCL18, Human
HY-P7265 50ug
EUR 533

MIP-4 Recombinant Protein
40-385-0002mg 0.002 mg
EUR 259.25
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-4 Recombinant Protein
40-385-001mg 0.01 mg
EUR 364.25
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Sheep MIP-4 ELISA Kit
ESM0021 96Tests
EUR 521

Monkey MIP-4 ELISA Kit
EMKM0021 96Tests
EUR 521

Mouse MIP-4 ELISA Kit
EMM0021 96Tests
EUR 521

Porcine MIP-4 ELISA Kit
EPM0021 96Tests
EUR 521

Rat MIP-4 ELISA Kit
ERM0021 96Tests
EUR 521

Rabbit MIP-4 ELISA Kit
ERTM0021 96Tests
EUR 521

Anserini MIP-4 ELISA Kit
EAM0021 96Tests
EUR 521

Goat MIP-4 ELISA Kit
EGTM0021 96Tests
EUR 521

Chicken MIP-4 ELISA Kit
ECKM0021 96Tests
EUR 521

Canine MIP-4 ELISA Kit
ECM0021 96Tests
EUR 521

Human MIP-4 ELISA Kit
EHM0021 96Tests
EUR 521

Bovine MIP-4 ELISA Kit
EBM0021 96Tests
EUR 521

MIP-4, PARC, CCL18, human
RC315-29 2ug
EUR 104.38

MIP-4 (PARC), human recombinant
4257-10
EUR 338

MIP-4 (PARC), human recombinant
4257-1000
EUR 5917

Guinea Pig MIP-4 ELISA Kit
EGM0021 96Tests
EUR 521

Recombinant Human MIP-4 (CCL18) Protein
PROTP55774-2 10ug
EUR 317
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Individual Reaction Mix 4
G065-4 200 reactions
EUR 167

rHu Insulin
AK8211-0025 25mg Ask for price

rHu Insulin
AK8211-0250 250mg Ask for price

rHu Insulin
AK8211-1000 1g Ask for price

rHu aFGF
AK8230-0010 10µg Ask for price

rHu aFGF
AK8230-0050 50µg Ask for price

rHu aFGF
AK8230-0100 100µg Ask for price

rHu aFGF
AK8230-1000 1mg Ask for price

rHu MCSF
AK8238-0002 2µg Ask for price

rHu MCSF
AK8238-0010 10µg Ask for price

rHu MCSF
AK8238-0100 100µg Ask for price

rHu MCSF
AK8238-1000 1mg Ask for price

rHu CTGF
AK8240-0005 5µg Ask for price

rHu CTGF
AK8240-0020 20µg Ask for price

rHu CTGF
AK8240-0100 100µg Ask for price

rHu CTGF
AK8240-1000 1mg Ask for price

rHu MIF
AK8255-0005 5µg Ask for price

rHu MIF
AK8255-0025 25µg Ask for price

rHu MIF
AK8255-0100 100µg Ask for price

rHu MIF
AK8255-1000 1mg Ask for price

rHu Myostatin
AK8256-0002 2µg Ask for price

rHu Myostatin
AK8256-0010 10µg Ask for price

rHu Myostatin
AK8256-0100 100µg Ask for price

rHu Myostatin
AK8256-1000 1mg Ask for price

rHu Leptin
AK8265-0200 200µg Ask for price

rHu Leptin
AK8265-1000 1mg Ask for price

rHu Leptin
AK8265-5000 5mg Ask for price

rHu RANTES
AK8275-0005 5µg Ask for price

rHu RANTES
AK8275-0020 20µg Ask for price

rHu RANTES
AK8275-0100 100µg Ask for price

rHu RANTES
AK8275-1000 1mg Ask for price

rHu BDNF
AK8286-0002 2µg Ask for price

rHu BDNF
AK8286-0010 10µg Ask for price

rHu BDNF
AK8286-0100 100µg Ask for price

rHu BDNF
AK8286-1000 1mg Ask for price

rHu CNTF
AK8302-0005 5µg Ask for price

rHu CNTF
AK8302-0020 20µg Ask for price

rHu CNTF
AK8302-0100 100µg Ask for price

rHu CNTF
AK8302-1000 1mg Ask for price

rHu EGF
AK8327-0100 100µg Ask for price

rHu EGF
AK8327-0500 500µg Ask for price

Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults

Humanin (HN) is a 24-amino acid mitochondrial-derived peptide, best known for its ability to protect neurons from damage caused by ischemic stroke and neurodegenerative insults and cardiomyocytes from myocardial infarction or doxorubicin (Dox)-induced cardiotoxicity.
This study examines the neuroprotective and myoprotective effects of HN novel synthetic analogs HUJInin and c(d-ser14)HN, prepared by solid-phase peptide synthesis. The cellular models employed were oxygen-glucose-deprivation (OGD) followed by reoxygenation (R)-induced neurotoxicity in PC12 and SH-SY5Y neuronal cell cultures and Dox-induced cardiotoxicity in H9c2 and C2C12 myoblast cell cultures, respectively.
Necrotic and apoptotic cell death was measured by LDH release and caspase-3 activity. Erk 1/2 and AKT phosphorylations were examined by western blotting. Mitochondrial calcium and mitochondrial membrane potential were measured using the fluorescent dye tetramethylrhodamine-methyl ester. It was found that HUJInin and c(d-ser14)HN conferred significant dose-dependent neuroprotection, a phenomenon related to attenuation of OGD insult-induced Erk 1/2 phosphorylation, stimulation of AKT phosphorylation and improvement of mitochondrial functions.
These peptides also conferred myoprotective effect towards (Dox)-induced apo-necrotic cell death insults. HUJInin and c(d-ser14)HN synthetic analogs may provide new lead compounds for the development of a potential candidate drug for stroke treatment and/or DOX-induced cardiotoxicity therapy in cancer patients.

Enhancing the Furosemide Permeability by Papain Minitablets Through a Triple Co-culture In Vitro Intestinal Cell Model

The administration of medicines by the oral route is the most used approach for being very convenient. Although it is the most popular, this route also has absorption, and consequently, bioavailability limitations. In this sense, several pharmacotechnical strategies have been used to improve drug absorption, one of which is the use of permeation promoters.
Papain is a very versatile plant enzyme that can be used as a permeation promoter of various active compounds. This study aimed to evaluate the safety of papain and the formulation of native papain minitablets to promote in vitro permeation of furosemide through an innovative biomimetic triple co-culture model of Caco-2, HT29-MTX, and Raji cells.
Regarding permeation, furosemide and metaprolol concentrations are determined with HPLC; those are used to calculate Papp. Monolayer integrity was evaluated using TEER and Lucifer Yellow. In the presence of papain, TEER decreased two-fold and the Papp of furosemide increased six-fold.
The results suggest that native papain minitablets can be used as therapeutic adjuvants to enhance the permeation of drugs significantly improving bioavailability.

MIP-3 beta Recombinant Protein
40-381-0005mg 0.005 mg
EUR 259.25
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 beta Recombinant Protein
40-381-002mg 0.02 mg
EUR 364.25
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 beta, CCL19, murine (mouse)
RC335-20 5ug
EUR 101.33

Anti-MIP- beta antibody
STJ96572 200 µl
EUR 197
Description: Rabbit polyclonal to MIP-1beta.

Anti-MIP- beta antibody
STJ94131 200 µl
EUR 197
Description: Rabbit polyclonal to MIP-3beta.

rHu MIP-1-beta
AK8264-0002 2µg Ask for price

rHu MIP-1-beta
AK8264-0010 10µg Ask for price

rHu MIP-1-beta
AK8264-0100 100µg Ask for price

rHu MIP-1-beta
AK8264-1000 1mg Ask for price

MIP-1-beta Antibody
5249-100
EUR 338

MIP 1 beta antibody
20R-1789 100 ug
EUR 673
Description: Rabbit polyclonal MIP 1 beta antibody

rM IL-2
AK8323-0005 5µg Ask for price

rM IL-2
AK8323-0020 20µg Ask for price

rM IL-2
AK8323-0100 100µg Ask for price

rM IL-2
AK8323-1000 1mg Ask for price

Recombinant Human MIP-3 Beta (CCL19) Protein
PROTQ99731-1 20ug
EUR 317
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Murine MIP-3 Beta (CCL19) Protein
PROTO70460-2 20ug
EUR 317
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Human CCL19/MIP-3 beta ELISA Kit
LF-EK50840 1×96T
EUR 648

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody
M02431-3 100ug/vial
EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

MIP-3
EF017888 96 Tests
EUR 689

MIP-3
EF013760 96 Tests
EUR 689

MIP-3
EF013761 96 Tests
EUR 689

MIP-3
EF016652 96 Tests
EUR 689

MIP-3
EF016984 96 Tests
EUR 689

MIP-3
EF010865 96 Tests
EUR 689

MIP-3
EF012726 96 Tests
EUR 689

MIP-3
PAab09791 100 ug
EUR 386

1 mm Gaskets 3/pk, RM
2398237 5unit
EUR 257

MIP-1 beta, CCL4, human
RC314-15 2ug
EUR 101.33

MIP-1 beta, CCL4, rat
RC355-15 5ug
EUR 104.38

MIP-1-beta/CCL4, Human
HY-P7257 10ug
EUR 268

MIP-1 beta Recombinant Protein
40-358-0002mg 0.002 mg
EUR 259.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein
40-358-001mg 0.01 mg
EUR 364.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein
40-365-0002mg 0.002 mg
EUR 259.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein
40-365-001mg 0.01 mg
EUR 364.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein
40-407-0005mg 0.005 mg
EUR 259.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-1 beta Recombinant Protein
40-407-002mg 0.02 mg
EUR 364.25
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Clips 4/pk RM
2398239 6unit
EUR 250

1mm Pressure Platen - RM
2398242 3unit
EUR 281

Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody
M01605 100ug/vial
EUR 397
Description: Rabbit Monoclonal CCL19/Mip 3 Beta Antibody. Validated in WB and tested in Human.

Rabbit Anti Human Mip-3 Beta Polyclonal Antibody
CPBT-65218RH 0.1 mg
EUR 881

ELISA kit for Human CCL19/MIP-3 Beta
EK5194 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CCL19/MIP-3 Beta in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse CCL19/MIP-3 beta
EK5195 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CCL19/MIP-3 beta in samples from serum, plasma, tissue homogenates and other biological fluids.

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant
PROTP10600-3 Regular: 5ug
EUR 317
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

anti- MIP-3
LSMab09791 100 ug
EUR 386

Anti-IL1 beta Antibody
A00101-3 100ug
EUR 455
Description: Rabbit Polyclonal IL1 beta Antibody. Validated in IP, IF, IHC, WB and tested in Mouse, Rat.

MIP-1 beta, CCL4, murine (mouse)
RC335-15 2ug
EUR 104.38

Pig MIP-1 Beta (CCL4) Protein
abx670310-5ug 5 ug
EUR 411

GRO beta / MIP-2 (CXCL2) Protein
20-abx261572
  • EUR 328.00
  • EUR 3418.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

GRO beta / MIP-2 (CXCL2) Protein
20-abx261590
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

GRO beta / MIP-2 (CXCL2) Protein
20-abx261604
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

MIP-1 beta (human) ELISA Kit
K4785-100 100 assays
EUR 809
Description: Sensitive, Colorimetric Assay

GRO-beta/MIP-2, rat recombinant
4108-1000
EUR 3965

GRO-beta/MIP-2, rat recombinant
4108-20
EUR 262

MIP-2/Gro-beta, murine recombinant
4251-1000
EUR 5204

MIP-2/Gro-beta, murine recombinant
4251-20
EUR 297

Rabbit Anti Human Mip-3 Beta Polyclonal Antibody,Biotin
CPBT-65217RH 50 µg
EUR 881

1 mm Preparative Comb, RM
2328934 3unit
EUR 253
Description: 1 sampl e wel l and 1 r efer ence wel l

0.75mm Plate Set,RM-075
2393014 2unit
EUR 263
Description: 1 pai r of gl ass pl at es + 1 gask et , for 0.75 mm gel

5 mm Dummy Plate, RM
2393074 10unit
EUR 241
Description: Pl ast i c pl at e for r unni ng 1 Pagel pr ecast gel onl y

2mm Plate Set,RM-22
2393740 3unit
EUR 281
Description: 1 pai r of gl ass pl at es + 1 gask et , for 2 mm gel

7 mm Dummy Plate, RM
2398247 10unit
EUR 241
Description: Pl ast i c pl at e for r unni ng 1 hand-cast gel onl y

1 mm Blank Comb, RM
2399041 4unit
EUR 272

Anti- Beta-tubulin Monoclonal Antibody
M05613-3 100ul
EUR 397
Description: Mouse Monoclonal Beta-tubulin Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat.

Recombinant Human IFN-Beta Protein
PROTP01574-3 20ug
EUR 317
Description: Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFNβ. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNα contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNβ is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNβ has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.

*Human IFN-β(Catalog Number 300-02BC) has replaced Human IFN-β(Catalog Number 300-02B)

Swine IFN beta Recombinant Protein
R02041-3 5ug/vial
EUR 259
Description: IFN beta is a mammalian Type I interferon, functioning as a regulator of cellular activity by interacting with cell-surface receptors and activating various signaling pathways. IFN beta produces antiviral, antibacterial, and anticancer properties. Swine IFN beta Recombinant Protein is purified IFN beta produced in yeast.

Anti-GLB1/Beta-galactosidase Antibody
A01829-3 100ug/vial
EUR 334

Anti-Beta Tubulin Antibody (monoclonal, 5E4)
M01857-3 100ug/vial
EUR 294

Recombinant Human IL-1 Beta Protein
PROTP01584-3 10ug
EUR 317
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.

Equine IL-1 beta Recombinant Protein
R00101-3 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Equine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Anti-beta 2 Microglobulin/B2m Antibody
A00456-3 100ug/vial
EUR 294

MIP-3? Polyclonal Antibody
ES8712-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against MIP-3? from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

MIP-3? Polyclonal Antibody
ES8712-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against MIP-3? from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

MIP-3? Polyclonal Antibody
ES7130-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against MIP-3? from Human. This antibody is tested and validated for IHC, WB, ELISA

MIP-3? Polyclonal Antibody
ES7130-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against MIP-3? from Human. This antibody is tested and validated for IHC, WB, ELISA

MIP-3, CCL23, human
RC315-34 5ug
EUR 104.38

rHu MIP-3-alpha
AK8271-0005 5µg Ask for price

rHu MIP-3-alpha
AK8271-0020 20µg Ask for price

rHu MIP-3-alpha
AK8271-0100 100µg Ask for price

rHu MIP-3-alpha
AK8271-1000 1mg Ask for price

MIP-3 Recombinant Protein
40-379-0005mg 0.005 mg
EUR 259.25
Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

MIP-3 Recombinant Protein
40-379-002mg 0.02 mg
EUR 364.25
Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-100ug
QP10273-ec-100ug 100ug
EUR 988

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-20ug
QP10273-ec-20ug 20ug
EUR 290

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-250ug
QP10273-ec-250ug 250ug
EUR 1731

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-5ug
QP10273-ec-5ug 5ug
EUR 154

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-1mg
QP5219-1mg 1mg
EUR 2856

Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-500ug
QP5219-500ug 500ug
EUR 1778

Recombinant Human MIP-3 beta/ CCL19 Protein, Untagged, E.coli-100ug
QP5258-100ug 100ug
EUR 490

Recombinant Human MIP-3 beta/ CCL19 Protein, Untagged, E.coli-1mg
QP5258-1mg 1mg
EUR 2856

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