
DEP-Dots for 3D cell culture: low-cost, high-repeatability, effective 3D cell culture in multiple gel systems
It is known that cells grown in 3D are more tolerant to drug treatment than those grown in dispersion, but the mechanism for this is still not clear; cells grown in 3D have opportunities to develop inter-cell communication, but are also closely packed which may impede diffusion.
In this study we examine methods for dielectrophoresis-based cell aggregation of both suspension and adherent cell lines, and compare the effect of various drugs on cells grown in 3D and 2D. Comparing viability of pharmacological interventions on 3D cell clusters against both suspension cells and adherent cells grown in monolayer, as well as against a unicellular organism with no propensity for intracellular communication, we suggest that 3D aggregates of adherent cells, compared to suspension cells, show a substantially different drug response to cells grown in monolayer, which increases as the IC50 is approached.
Further, a mathematical model of the system for each agent demonstrates that changes to drug response are due to inherent changes in the system of adherent cells from the 2D to 3D state. Finally, differences in the electrophysiological membrane properties of the adherent cell type suggest this parameter plays an important role in the differences found in the 3D drug response.

pharmacodane
rHu MIP-3-beta |
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AK8232-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-3-beta |
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AK8232-1000 | Akron Biotech | 1mg | Ask for price |
rHu MIP-1-alpha |
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AK8250-0005 | Akron Biotech | 5µg | Ask for price |
rHu MIP-1-alpha |
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AK8250-0020 | Akron Biotech | 20µg | Ask for price |
rHu MIP-1-alpha |
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AK8250-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-1-alpha |
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AK8250-1000 | Akron Biotech | 1mg | Ask for price |
rHu MIP-1-beta |
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AK8264-0002 | Akron Biotech | 2µg | Ask for price |
rHu MIP-1-beta |
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AK8264-0010 | Akron Biotech | 10µg | Ask for price |
rHu MIP-1-beta |
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AK8264-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-1-beta |
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AK8264-1000 | Akron Biotech | 1mg | Ask for price |
rHu MIP-3-alpha |
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AK8271-0005 | Akron Biotech | 5µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-0020 | Akron Biotech | 20µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-1000 | Akron Biotech | 1mg | Ask for price |
rHu IL-4 |
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AK8329-0005 | Akron Biotech | 5µg | Ask for price |
rHu IL-4 |
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AK8329-0020 | Akron Biotech | 20µg | Ask for price |
rHu IL-4 |
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AK8329-0100 | Akron Biotech | 100µg | Ask for price |
rHu IL-4 |
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AK8329-1000 | Akron Biotech | 1mg | Ask for price |
rHu MCP-4 |
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AK8332-0005 | Akron Biotech | 5µg | Ask for price |
rHu MCP-4 |
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AK8332-0020 | Akron Biotech | 20µg | Ask for price |
rHu MCP-4 |
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AK8332-0100 | Akron Biotech | 100µg | Ask for price |
rHu MCP-4 |
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AK8332-1000 | Akron Biotech | 1mg | Ask for price |
rHu FGF-4 |
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AK9698-0005 | Akron Biotech | 5µg | Ask for price |
rHu FGF-4 |
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AK9698-0025 | Akron Biotech | 25µg | Ask for price |
rHu FGF-4 |
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AK9698-0100 | Akron Biotech | 100µg | Ask for price |
rHu FGF-4 |
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AK9698-1000 | Akron Biotech | 1mg | Ask for price |
rHu IL-4 (cGMP) |
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AK9839-0000 | Akron Biotech | 1mg | Ask for price |
rHu IL-4 (cGMP) |
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AK9839-0100 | Akron Biotech | 100ug | Ask for price |
rHu BMP-4 (CHO) |
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AK9996-0005 | Akron Biotech | 5µg | Ask for price |
rHu BMP-4 (CHO) |
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AK9996-0020 | Akron Biotech | 20µg | Ask for price |
rHu BMP-4 (CHO) |
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AK9996-0100 | Akron Biotech | 100µg | Ask for price |
rHu BMP-4 (CHO) |
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AK9996-1000 | Akron Biotech | 1mg | Ask for price |
MIP-4/CCL18, Human |
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HY-P7265 | MedChemExpress | 50ug | EUR 533 |
MIP-4 Recombinant Protein |
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40-385-0002mg | ProSci | 0.002 mg | EUR 259.25 |
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-4 Recombinant Protein |
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40-385-001mg | ProSci | 0.01 mg | EUR 364.25 |
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Sheep MIP-4 ELISA Kit |
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ESM0021 | Abclonal | 96Tests | EUR 521 |
Monkey MIP-4 ELISA Kit |
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EMKM0021 | Abclonal | 96Tests | EUR 521 |
Mouse MIP-4 ELISA Kit |
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EMM0021 | Abclonal | 96Tests | EUR 521 |
Porcine MIP-4 ELISA Kit |
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EPM0021 | Abclonal | 96Tests | EUR 521 |
Rat MIP-4 ELISA Kit |
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ERM0021 | Abclonal | 96Tests | EUR 521 |
Rabbit MIP-4 ELISA Kit |
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ERTM0021 | Abclonal | 96Tests | EUR 521 |
Anserini MIP-4 ELISA Kit |
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EAM0021 | Abclonal | 96Tests | EUR 521 |
Goat MIP-4 ELISA Kit |
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EGTM0021 | Abclonal | 96Tests | EUR 521 |
Chicken MIP-4 ELISA Kit |
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ECKM0021 | Abclonal | 96Tests | EUR 521 |
Canine MIP-4 ELISA Kit |
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ECM0021 | Abclonal | 96Tests | EUR 521 |
Human MIP-4 ELISA Kit |
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EHM0021 | Abclonal | 96Tests | EUR 521 |
Bovine MIP-4 ELISA Kit |
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EBM0021 | Abclonal | 96Tests | EUR 521 |
MIP-4, PARC, CCL18, human |
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RC315-29 | Bio Basic | 2ug | EUR 104.38 |
MIP-4 (PARC), human recombinant |
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4257-10 | Biovision | EUR 338 |
MIP-4 (PARC), human recombinant |
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4257-1000 | Biovision | EUR 5917 |
Guinea Pig MIP-4 ELISA Kit |
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EGM0021 | Abclonal | 96Tests | EUR 521 |
Recombinant Human MIP-4 (CCL18) Protein |
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PROTP55774-2 | BosterBio | 10ug | EUR 317 |
Description: MIP-4 is a CC chemokine that is expressed in lymph nodes, lungs, placenta and bone marrow. MIP-4's primary receptor is unknown. MIP-4 chemoattracts lymphocytes, and has been shown to exert activity on both CD4+ and CD8+ T cells. Recombinant human MIP-4 is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
IL-4 Interleukin 4 Human Recombinant Protein, Yeast |
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PROTP05112-4 | BosterBio | Regular: 10ug | EUR 317 |
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques. |
Individual Reaction Mix 4 |
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G065-4 | ABM | 200 reactions | EUR 167 |
rHu Insulin |
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AK8211-0025 | Akron Biotech | 25mg | Ask for price |
rHu Insulin |
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AK8211-0250 | Akron Biotech | 250mg | Ask for price |
rHu Insulin |
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AK8211-1000 | Akron Biotech | 1g | Ask for price |
rHu aFGF |
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AK8230-0010 | Akron Biotech | 10µg | Ask for price |
rHu aFGF |
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AK8230-0050 | Akron Biotech | 50µg | Ask for price |
rHu aFGF |
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AK8230-0100 | Akron Biotech | 100µg | Ask for price |
rHu aFGF |
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AK8230-1000 | Akron Biotech | 1mg | Ask for price |
rHu MCSF |
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AK8238-0002 | Akron Biotech | 2µg | Ask for price |
rHu MCSF |
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AK8238-0010 | Akron Biotech | 10µg | Ask for price |
rHu MCSF |
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AK8238-0100 | Akron Biotech | 100µg | Ask for price |
rHu MCSF |
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AK8238-1000 | Akron Biotech | 1mg | Ask for price |
rHu CTGF |
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AK8240-0005 | Akron Biotech | 5µg | Ask for price |
rHu CTGF |
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AK8240-0020 | Akron Biotech | 20µg | Ask for price |
rHu CTGF |
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AK8240-0100 | Akron Biotech | 100µg | Ask for price |
rHu CTGF |
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AK8240-1000 | Akron Biotech | 1mg | Ask for price |
rHu MIF |
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AK8255-0005 | Akron Biotech | 5µg | Ask for price |
rHu MIF |
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AK8255-0025 | Akron Biotech | 25µg | Ask for price |
rHu MIF |
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AK8255-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIF |
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AK8255-1000 | Akron Biotech | 1mg | Ask for price |
rHu Myostatin |
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AK8256-0002 | Akron Biotech | 2µg | Ask for price |
rHu Myostatin |
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AK8256-0010 | Akron Biotech | 10µg | Ask for price |
rHu Myostatin |
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AK8256-0100 | Akron Biotech | 100µg | Ask for price |
rHu Myostatin |
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AK8256-1000 | Akron Biotech | 1mg | Ask for price |
rHu Leptin |
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AK8265-0200 | Akron Biotech | 200µg | Ask for price |
rHu Leptin |
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AK8265-1000 | Akron Biotech | 1mg | Ask for price |
rHu Leptin |
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AK8265-5000 | Akron Biotech | 5mg | Ask for price |
rHu RANTES |
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AK8275-0005 | Akron Biotech | 5µg | Ask for price |
rHu RANTES |
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AK8275-0020 | Akron Biotech | 20µg | Ask for price |
rHu RANTES |
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AK8275-0100 | Akron Biotech | 100µg | Ask for price |
rHu RANTES |
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AK8275-1000 | Akron Biotech | 1mg | Ask for price |
rHu BDNF |
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AK8286-0002 | Akron Biotech | 2µg | Ask for price |
rHu BDNF |
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AK8286-0010 | Akron Biotech | 10µg | Ask for price |
rHu BDNF |
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AK8286-0100 | Akron Biotech | 100µg | Ask for price |
rHu BDNF |
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AK8286-1000 | Akron Biotech | 1mg | Ask for price |
rHu CNTF |
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AK8302-0005 | Akron Biotech | 5µg | Ask for price |
rHu CNTF |
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AK8302-0020 | Akron Biotech | 20µg | Ask for price |
rHu CNTF |
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AK8302-0100 | Akron Biotech | 100µg | Ask for price |
rHu CNTF |
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AK8302-1000 | Akron Biotech | 1mg | Ask for price |
rHu EGF |
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AK8327-0100 | Akron Biotech | 100µg | Ask for price |
rHu EGF |
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AK8327-0500 | Akron Biotech | 500µg | Ask for price |
Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults
Humanin (HN) is a 24-amino acid mitochondrial-derived peptide, best known for its ability to protect neurons from damage caused by ischemic stroke and neurodegenerative insults and cardiomyocytes from myocardial infarction or doxorubicin (Dox)-induced cardiotoxicity.
This study examines the neuroprotective and myoprotective effects of HN novel synthetic analogs HUJInin and c(d-ser14)HN, prepared by solid-phase peptide synthesis. The cellular models employed were oxygen-glucose-deprivation (OGD) followed by reoxygenation (R)-induced neurotoxicity in PC12 and SH-SY5Y neuronal cell cultures and Dox-induced cardiotoxicity in H9c2 and C2C12 myoblast cell cultures, respectively.
Necrotic and apoptotic cell death was measured by LDH release and caspase-3 activity. Erk 1/2 and AKT phosphorylations were examined by western blotting. Mitochondrial calcium and mitochondrial membrane potential were measured using the fluorescent dye tetramethylrhodamine-methyl ester. It was found that HUJInin and c(d-ser14)HN conferred significant dose-dependent neuroprotection, a phenomenon related to attenuation of OGD insult-induced Erk 1/2 phosphorylation, stimulation of AKT phosphorylation and improvement of mitochondrial functions.
These peptides also conferred myoprotective effect towards (Dox)-induced apo-necrotic cell death insults. HUJInin and c(d-ser14)HN synthetic analogs may provide new lead compounds for the development of a potential candidate drug for stroke treatment and/or DOX-induced cardiotoxicity therapy in cancer patients.
Enhancing the Furosemide Permeability by Papain Minitablets Through a Triple Co-culture In Vitro Intestinal Cell Model
The administration of medicines by the oral route is the most used approach for being very convenient. Although it is the most popular, this route also has absorption, and consequently, bioavailability limitations. In this sense, several pharmacotechnical strategies have been used to improve drug absorption, one of which is the use of permeation promoters.
Papain is a very versatile plant enzyme that can be used as a permeation promoter of various active compounds. This study aimed to evaluate the safety of papain and the formulation of native papain minitablets to promote in vitro permeation of furosemide through an innovative biomimetic triple co-culture model of Caco-2, HT29-MTX, and Raji cells.
Regarding permeation, furosemide and metaprolol concentrations are determined with HPLC; those are used to calculate Papp. Monolayer integrity was evaluated using TEER and Lucifer Yellow. In the presence of papain, TEER decreased two-fold and the Papp of furosemide increased six-fold.
The results suggest that native papain minitablets can be used as therapeutic adjuvants to enhance the permeation of drugs significantly improving bioavailability.
MIP-3 beta Recombinant Protein |
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40-381-0005mg | ProSci | 0.005 mg | EUR 259.25 |
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 beta Recombinant Protein |
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40-381-002mg | ProSci | 0.02 mg | EUR 364.25 |
Description: MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 beta, CCL19, murine (mouse) |
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RC335-20 | Bio Basic | 5ug | EUR 101.33 |
Anti-MIP- beta antibody |
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STJ96572 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to MIP-1beta. |
Anti-MIP- beta antibody |
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STJ94131 | St John's Laboratory | 200 µl | EUR 197 |
Description: Rabbit polyclonal to MIP-3beta. |
rHu MIP-1-beta |
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AK8264-0002 | Akron Biotech | 2µg | Ask for price |
rHu MIP-1-beta |
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AK8264-0010 | Akron Biotech | 10µg | Ask for price |
rHu MIP-1-beta |
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AK8264-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-1-beta |
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AK8264-1000 | Akron Biotech | 1mg | Ask for price |
MIP-1-beta Antibody |
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5249-100 | Biovision | EUR 338 |
MIP 1 beta antibody |
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20R-1789 | Fitzgerald | 100 ug | EUR 673 |
Description: Rabbit polyclonal MIP 1 beta antibody |
rM IL-2 |
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AK8323-0005 | Akron Biotech | 5µg | Ask for price |
rM IL-2 |
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AK8323-0020 | Akron Biotech | 20µg | Ask for price |
rM IL-2 |
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AK8323-0100 | Akron Biotech | 100µg | Ask for price |
rM IL-2 |
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AK8323-1000 | Akron Biotech | 1mg | Ask for price |
Recombinant Human MIP-3 Beta (CCL19) Protein |
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PROTQ99731-1 | BosterBio | 20ug | EUR 317 |
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Recombinant Murine MIP-3 Beta (CCL19) Protein |
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PROTO70460-2 | BosterBio | 20ug | EUR 317 |
Description: MIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Human CCL19/MIP-3 beta ELISA Kit |
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LF-EK50840 | Abfrontier | 1×96T | EUR 648 |
Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody |
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M02431-3 | BosterBio | 100ug/vial | EUR 397 |
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
MIP-3 |
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EF017888 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF013760 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF013761 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF016652 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF016984 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF010865 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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EF012726 | Lifescience Market | 96 Tests | EUR 689 |
MIP-3 |
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PAab09791 | Lifescience Market | 100 ug | EUR 386 |
1 mm Gaskets 3/pk, RM |
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2398237 | Atto | 5unit | EUR 257 |
MIP-1 beta, CCL4, human |
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RC314-15 | Bio Basic | 2ug | EUR 101.33 |
MIP-1 beta, CCL4, rat |
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RC355-15 | Bio Basic | 5ug | EUR 104.38 |
MIP-1-beta/CCL4, Human |
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HY-P7257 | MedChemExpress | 10ug | EUR 268 |
MIP-1 beta Recombinant Protein |
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40-358-0002mg | ProSci | 0.002 mg | EUR 259.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 beta Recombinant Protein |
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40-358-001mg | ProSci | 0.01 mg | EUR 364.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant murine MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 beta Recombinant Protein |
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40-365-0002mg | ProSci | 0.002 mg | EUR 259.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 beta Recombinant Protein |
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40-365-001mg | ProSci | 0.01 mg | EUR 364.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant human MIP-1 betais a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 beta Recombinant Protein |
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40-407-0005mg | ProSci | 0.005 mg | EUR 259.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-1 beta Recombinant Protein |
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40-407-002mg | ProSci | 0.02 mg | EUR 364.25 |
Description: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1 alpha and MIP-1 beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1 beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Clips 4/pk RM |
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2398239 | Atto | 6unit | EUR 250 |
1mm Pressure Platen - RM |
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2398242 | Atto | 3unit | EUR 281 |
Anti-CCL19/Mip 3 Beta Rabbit Monoclonal Antibody |
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M01605 | BosterBio | 100ug/vial | EUR 397 |
Description: Rabbit Monoclonal CCL19/Mip 3 Beta Antibody. Validated in WB and tested in Human. |
Rabbit Anti Human Mip-3 Beta Polyclonal Antibody |
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CPBT-65218RH | Creative Diagnostics | 0.1 mg | EUR 881 |
ELISA kit for Human CCL19/MIP-3 Beta |
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EK5194 | SAB | 96 tests | EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CCL19/MIP-3 Beta in samples from serum, plasma, tissue homogenates and other biological fluids. |
ELISA kit for Mouse CCL19/MIP-3 beta |
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EK5195 | SAB | 96 tests | EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CCL19/MIP-3 beta in samples from serum, plasma, tissue homogenates and other biological fluids. |
TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant |
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PROTP10600-3 | BosterBio | Regular: 5ug | EUR 317 |
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques. |
anti- MIP-3 |
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LSMab09791 | Lifescience Market | 100 ug | EUR 386 |
Anti-IL1 beta Antibody |
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A00101-3 | BosterBio | 100ug | EUR 455 |
Description: Rabbit Polyclonal IL1 beta Antibody. Validated in IP, IF, IHC, WB and tested in Mouse, Rat. |
MIP-1 beta, CCL4, murine (mouse) |
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RC335-15 | Bio Basic | 2ug | EUR 104.38 |
Pig MIP-1 Beta (CCL4) Protein |
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abx670310-5ug | Abbexa | 5 ug | EUR 411 |
GRO beta / MIP-2 (CXCL2) Protein |
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20-abx261572 | Abbexa |
|
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GRO beta / MIP-2 (CXCL2) Protein |
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20-abx261590 | Abbexa |
|
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GRO beta / MIP-2 (CXCL2) Protein |
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20-abx261604 | Abbexa |
|
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MIP-1 beta (human) ELISA Kit |
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K4785-100 | Biovision | 100 assays | EUR 809 |
Description: Sensitive, Colorimetric Assay |
GRO-beta/MIP-2, rat recombinant |
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4108-1000 | Biovision | EUR 3965 |
GRO-beta/MIP-2, rat recombinant |
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4108-20 | Biovision | EUR 262 |
MIP-2/Gro-beta, murine recombinant |
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4251-1000 | Biovision | EUR 5204 |
MIP-2/Gro-beta, murine recombinant |
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4251-20 | Biovision | EUR 297 |
Rabbit Anti Human Mip-3 Beta Polyclonal Antibody,Biotin |
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CPBT-65217RH | Creative Diagnostics | 50 µg | EUR 881 |
1 mm Preparative Comb, RM |
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2328934 | Atto | 3unit | EUR 253 |
Description: 1 sampl e wel l and 1 r efer ence wel l |
0.75mm Plate Set,RM-075 |
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2393014 | Atto | 2unit | EUR 263 |
Description: 1 pai r of gl ass pl at es + 1 gask et , for 0.75 mm gel |
5 mm Dummy Plate, RM |
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2393074 | Atto | 10unit | EUR 241 |
Description: Pl ast i c pl at e for r unni ng 1 Pagel pr ecast gel onl y |
2mm Plate Set,RM-22 |
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2393740 | Atto | 3unit | EUR 281 |
Description: 1 pai r of gl ass pl at es + 1 gask et , for 2 mm gel |
7 mm Dummy Plate, RM |
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2398247 | Atto | 10unit | EUR 241 |
Description: Pl ast i c pl at e for r unni ng 1 hand-cast gel onl y |
1 mm Blank Comb, RM |
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2399041 | Atto | 4unit | EUR 272 |
Anti- Beta-tubulin Monoclonal Antibody |
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M05613-3 | BosterBio | 100ul | EUR 397 |
Description: Mouse Monoclonal Beta-tubulin Antibody. Validated in IHC, WB and tested in Human, Monkey, Mouse, Rat. |
Recombinant Human IFN-Beta Protein |
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PROTP01574-3 | BosterBio | 20ug | EUR 317 |
Description: Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFNβ. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNα contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNβ is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNβ has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry. *Human IFN-β(Catalog Number 300-02BC) has replaced Human IFN-β(Catalog Number 300-02B) |
Swine IFN beta Recombinant Protein |
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R02041-3 | BosterBio | 5ug/vial | EUR 259 |
Description: IFN beta is a mammalian Type I interferon, functioning as a regulator of cellular activity by interacting with cell-surface receptors and activating various signaling pathways. IFN beta produces antiviral, antibacterial, and anticancer properties. Swine IFN beta Recombinant Protein is purified IFN beta produced in yeast. |
Anti-GLB1/Beta-galactosidase Antibody |
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A01829-3 | BosterBio | 100ug/vial | EUR 334 |
Anti-Beta Tubulin Antibody (monoclonal, 5E4) |
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M01857-3 | BosterBio | 100ug/vial | EUR 294 |
Recombinant Human IL-1 Beta Protein |
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PROTP01584-3 | BosterBio | 10ug | EUR 317 |
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues. |
Equine IL-1 beta Recombinant Protein |
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R00101-3 | BosterBio | 5ug/vial | EUR 259 |
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Equine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
Anti-beta 2 Microglobulin/B2m Antibody |
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A00456-3 | BosterBio | 100ug/vial | EUR 294 |
MIP-3? Polyclonal Antibody |
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ES8712-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against MIP-3? from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA |
MIP-3? Polyclonal Antibody |
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ES8712-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against MIP-3? from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA |
MIP-3? Polyclonal Antibody |
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ES7130-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against MIP-3? from Human. This antibody is tested and validated for IHC, WB, ELISA |
MIP-3? Polyclonal Antibody |
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ES7130-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against MIP-3? from Human. This antibody is tested and validated for IHC, WB, ELISA |
MIP-3, CCL23, human |
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RC315-34 | Bio Basic | 5ug | EUR 104.38 |
rHu MIP-3-alpha |
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AK8271-0005 | Akron Biotech | 5µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-0020 | Akron Biotech | 20µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-0100 | Akron Biotech | 100µg | Ask for price |
rHu MIP-3-alpha |
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AK8271-1000 | Akron Biotech | 1mg | Ask for price |
MIP-3 Recombinant Protein |
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40-379-0005mg | ProSci | 0.005 mg | EUR 259.25 |
Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
MIP-3 Recombinant Protein |
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40-379-002mg | ProSci | 0.02 mg | EUR 364.25 |
Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-100ug |
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QP10273-ec-100ug | EnQuireBio | 100ug | EUR 988 |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-20ug |
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QP10273-ec-20ug | EnQuireBio | 20ug | EUR 290 |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-250ug |
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QP10273-ec-250ug | EnQuireBio | 250ug | EUR 1731 |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-5ug |
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QP10273-ec-5ug | EnQuireBio | 5ug | EUR 154 |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-1mg |
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QP5219-1mg | EnQuireBio | 1mg | EUR 2856 |
Recombinant Mouse MIP-3 beta/ CCL19 Protein, Untagged, E.coli-500ug |
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QP5219-500ug | EnQuireBio | 500ug | EUR 1778 |
Recombinant Human MIP-3 beta/ CCL19 Protein, Untagged, E.coli-100ug |
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QP5258-100ug | EnQuireBio | 100ug | EUR 490 |
Recombinant Human MIP-3 beta/ CCL19 Protein, Untagged, E.coli-1mg |
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QP5258-1mg | EnQuireBio | 1mg | EUR 2856 |