Scaffolds for 3D Cell Culture and Noninvasive

pharmacodane

Biocompliant Composite Au/pHEMA Plasmonic Scaffolds for 3D Cell Culture and Noninvasive Sensing of Cellular Metabolites

The field of 3D printing is an area of active research, with a substantial focus given to the design and construction of customized tools for applications in technology. There exists a particular need in these developing areas of opportunity for new multi-functional soft materials that are biologically compatible for the growth and directed culturing of cells. Herein, a composite material consisting of gold nanoparticles with useful plasmonic properties embedded within a highly hydrophilic poly-2-hydroxyethylmethacrylate matrix is described and characterized.
This composite material serves dual functions as both host framework scaffold for cell lines such as pre-osteoblasts as well as a plasmonic biosensor for in situ measurements of living cells. The plasmonic properties of this system are characterized as a function of the material properties and related to compositional features of the material through a proposed light-directed mechanism.
This chemistry provides a tunable, 3D printable plasmonic composite material of encapsulated gold nanoparticles in a biologically-compliant, acrylate-based hydrogel matrix. Surface-enhanced Raman scattering studies of 3D-microcultures supported by the scaffolds are carried out and the strong influence of perm-selective molecular diffusion in its analytical responses is established. Most notably, specific, largely hydrophilic, cellular metabolites are detected within the supported live cultures.
pharmacodane

pharmacodane

anti-Activator of basal transcription 1

YF-PA18596 50 ul
EUR 363
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1

YF-PA18597 50 ug
EUR 363
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1

YF-PA18598 50 ul
EUR 363
Description: Mouse polyclonal to Activator of basal transcription 1

anti-Activator of basal transcription 1

YF-PA18599 50 ug
EUR 363
Description: Mouse polyclonal to Activator of basal transcription 1

Activator of Basal Transcription 1 (ABT1) Antibody

20-abx110789
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Activator Of Basal Transcription 1 (ABT1) Antibody

20-abx338734
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator of Basal Transcription 1 (ABT1) Antibody

20-abx004524
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Activator of Basal Transcription 1 (ABT1) Antibody

abx037021-100ug 100 ug
EUR 391

Activator of Basal Transcription 1 (ABT1) Antibody

abx230056-100ug 100 ug
EUR 481

Activator Of Basal Transcription 1 (ABT1) Antibody (HRP)

20-abx334566
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator Of Basal Transcription 1 (ABT1) Antibody (FITC)

20-abx334567
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Activator Of Basal Transcription 1 (ABT1) Antibody (Biotin)

20-abx334568
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Activator Of Basal Transcription 1 (ABT1) ELISA Kit

abx385562-96tests 96 tests
EUR 911

Bovine Activator of basal transcription 1, ABT1 ELISA KIT

ELI-24538b 96 Tests
EUR 928

Mouse Activator of basal transcription 1, Abt1 ELISA KIT

ELI-24666m 96 Tests
EUR 865

Human Activator of basal transcription 1, ABT1 ELISA KIT

ELI-24776h 96 Tests
EUR 824

Human Activator of basal transcription 1(ABT1) ELISA kit

E01A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Activator of basal transcription 1(ABT1) ELISA kit

E01A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Activator of basal transcription 1(ABT1) ELISA kit

E01A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit

E04A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit

E04A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Activator of basal transcription 1(ABT1) ELISA kit

E04A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit

E03A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit

E03A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Activator of basal transcription 1(ABT1) ELISA kit

E03A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit

E02A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit

E02A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Activator of basal transcription 1(ABT1) ELISA kit

E02A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit

E07A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit

E07A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Activator of basal transcription 1(ABT1) ELISA kit

E07A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit

E06A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit

E06A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Activator of basal transcription 1(ABT1) ELISA kit

E06A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit

E08A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit

E08A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Activator of basal transcription 1(ABT1) ELISA kit

E08A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit

E09A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit

E09A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Activator of basal transcription 1(ABT1) ELISA kit

E09A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

BME 100X Amino Acids for Basal Medium Eagle (Modified). W/O L-glutamine.

BML02-500ML 500 ml
EUR 104
Description: 100X Amino Acids for Basal Medium Eagle (Modified). Without L-glutamine.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit

E05A1165-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit

E05A1165-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Activator of basal transcription 1(ABT1) ELISA kit

E05A1165-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Guinea pig Activator of basal transcription 1(ABT1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pericyte Basal Media

PGB002 475 ml
EUR 271

Astrocyte Basal Media

PGB004 500 ml
EUR 271

ENDO Basal Media

MED002 500 ml
EUR 207

Anderson's Basal Salt

CP001-010 10x1L
EUR 99

Anderson's Basal Salt

CP001-500 50L
EUR 126

Anderson's Basal Salt

CP002-010 10X1L
EUR 99

Anderson's Basal Salt

CP002-500 50L
EUR 126

500 ML GRACES'S INSECT BASAL MEDIUM (VAUGHN MOD.) WITH L-GLUTAMINE, WITHOUT INSECT HEMOLYMPH

13-200-CV 500 mL/pk
EUR 315
Description: Specialty Media; Insect Media Products

M9CA Medium

SD7025 250g
EUR 71.75

YM Medium

SD7031 250g
EUR 70.45

TYGPN Medium

SD7032 250g
EUR 70.01

M63 Medium

SD7033 250g
EUR 71.75

M9 Medium

SD7024 250g
EUR 71.75

A Medium

DJ1018 100g
EUR 84.8

NeuroProgenitor Medium

NM42400 125 ml
EUR 304

Heller's Medium

CP014-010 10X1L
EUR 99

Heller's Medium

CP014-500 50L
EUR 126

Hoagland's Medium

CP015-010 10X1L
EUR 99

Hoagland's Medium

CP015-500 50L
EUR 126

Advanced Medium

C0003-04 RT 500 mL Bottle
EUR 103

Medium 199

C0012-01 RT 500 mL Bottle
EUR 105

DC MEDIUM

D04-117-10kg 10 kg
EUR 1579

DC MEDIUM

D04-117-2kg 2kg
EUR 382

DC MEDIUM

D04-117-500g 500 g
EUR 140

HLP MEDIUM

H08-107-10kg 10 kg
EUR 2278

HLP MEDIUM

H08-107-2Kg 2 Kg
EUR 534

HLP MEDIUM

H08-107-500g 500 g
EUR 182

EC MEDIUM

E05-100-10kg 10 kg
EUR 814

EC MEDIUM

E05-100-2Kg 2 Kg
EUR 216

EC MEDIUM

E05-100-500g 500 g
EUR 95

COLIFORM MEDIUM

C03-127-10kg 10 kg
EUR 1324

COLIFORM MEDIUM

C03-127-2kg 2kg
EUR 327

COLIFORM MEDIUM

C03-127-500g 500 g
EUR 125

SIM MEDIUM

S19-110-10kg 10 kg
EUR 1021

SIM MEDIUM

S19-110-2kg 2kg
EUR 261

SIM MEDIUM

S19-110-500g 500 g
EUR 107

SOB MEDIUM

S19-124-10kg 10 kg
EUR 965

SOB MEDIUM

S19-124-2kg 2kg
EUR 249

SOB MEDIUM

S19-124-500g 500 g
EUR 104

DKW Basal Salt Mixture

CP007-010 10X1L
EUR 99

DKW Basal Salt Mixture

CP007-500 50L
EUR 126

ExpressMax™ Basal Salts

145 500 g
EUR 86

Basal Body Marker antibody

10-2480 250 ug
EUR 492
Description: Mouse monoclonal Basal Body Marker antibody

Basal Cell Cytokeratin antibody

10R-7959 100 ug
EUR 370
Description: Mouse monoclonal Basal Cell Cytokeratin antibody

Insect Cell Medium: TNM-FH Insect Culture Medium

ABP-MED-10001 1 liter Ask for price

Insect Cell Medium: Serum-Free Insect Culture Medium

ABP-MED-10002 1 liter Ask for price

Insect Cell Medium: Grace?s Insect Medium (Unsupplemented)

ABP-MED-10004 1 liter Ask for price

Cancer of the breast, basal-like breast carcinoma, 48 cases (1.5mm), set 1

BRC965 1
EUR 410
Description: Breast cancer tissue array, basal-like breast carcinoma, 48 cases (1.5mm), set 1, 96 cores, 48 cases, containing 35 cases basal-like, 3 cases luminal A, 3 cases luminal B, 4 cases Her2 overexpression types and 1 case Adenoid cystic carcinoma for positive control, with grading, TNM staging, and ER, PR, HER2, P53, EGFR, Ki67,CK5/6 and Nestin IHC data.

H Medium Broth

DJ1019 100g
EUR 60.88

Agarose, medium EEO

GE4750-100G 100 g
EUR 166

Expansion of mouse primitive hematopoietic cells in three-dimensional cultures on chemically fixed stromal cell layers

To establish a practical and convenient method to expand hematopoietic cells (HCs), we applied chemically-fixed stromal cell layers formed within three-dimensional (3D) scaffolds to feeder of HC cultures. The HCs were expanded using two successive cultures. First, stromal cells were cultured within porous polymer scaffolds and formed tissue-engineered constructs (TECs); the scaffolds containing stromal cells, were fixed using aldehyde (formaldehyde or glutaraldehyde) or organic solvents (acetone, methanol or ethanol).
Second, mouse fetal liver cells (FLCs), as a source of HCs, were cultured on the TECs for 2 weeks, and the effects of fixative solutions on expansion of primitive HCs (c-kit+ and CD34+ cells) were examined. In the cultures on aldehyde-fixed TECs, primitive HCs were expanded 2.5- to 5.1-fold in the cultures on TECs fixed with glutaraldehyde, whereas no expansions were detected in those fixed with formaldehyde.
However, we achieved expansion of primitive HCs > fivefold in the cultures using TECs fixed with organic solvents. Among these solvents, the highest expansions-of roughly tenfold-were obtained using acetone fixation. Ethanol-fixed TECs also supported the expansion of the primitive HCs well (6.6- to 8.0-fold). In addition to these sufficient expansions, the procedure and storage of fixed TECs is fairly easy. Thus, HC expansion on chemically-fixed TECs may be a practical method for expanding primitive HCs.
Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cellculture assays
3D cell culture assays are becoming increasingly popular due to their higher resemblance to tissue environment. These provide an increased complexity compared to the growth on 2D surface and therefore allow studies of advanced cellular properties such as invasion.
We report here on the use of 3D Matrigel cell preparations combined with a particular gentle and informative type of live-cell microscopy: quantitative digital holographic microscopy (DHM), here performed by a commercial software-integrated system, currently mostly used for 2D cell culture preparations. By demonstrating this compatibility, we highlight the possible time-efficient quantitative analysis obtained by using a commercial software-integrated DHM system, also for cells in a more advanced 3D culture environment.
Further, we demonstrate two very different examples making use of this advantage by performing quantitative DHM analysis of: (1) wound closure cell monolayer Matrigel invasion assay and (2) Matrigel-trapped single and clumps of suspension cells. For both these, we benefited from the autofocus functionality of digital phase holographic imaging to obtain 3D information for cells migrating in a 3D environment. For the latter, we demonstrate that it is possible to quantitatively measure tumourigenic properties like growth of cell clump (or spheroid) over time, as well as single-cell invasion out of cell clump and into the surrounding extracellular matrix.
Overall, our findings highlight several possibilities for 3D digital holographic microscopy applications combined with 3D cell preparations, therein studies of drug response or genetic alterations on invasion capacity as well as on tumour growth and metastasis.

OryzaExp? IGF-1 LR3, Human Recombinant

P1399-1
EUR 881

1 mm Preparative Comb, RM

2328934 3unit
EUR 253
Description: 1 sampl e wel l and 1 r efer ence wel l

1 mm Blank Comb, RM

2399041 4unit
EUR 272

rM IL-2

AK8323-0005 5µg Ask for price

rM IL-2

AK8323-0020 20µg Ask for price

rM IL-2

AK8323-0100 100µg Ask for price

rM IL-2

AK8323-1000 1mg Ask for price

IGF-II, human recombinant

P1017-1 1 mg
EUR 1998
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

1 mm 6-well Comb, RM

2328375 3unit
EUR 255

1 mm 8-well Comb, RM

2328376 3unit
EUR 255

1 mm 20-well Comb, RM

2328422 3unit
EUR 311

1 mm 10-well Comb, RM

2328948 3unit
EUR 288

1 mm Plate Set, RM-10

2398214 3unit
EUR 281
Description: 1 pai r of gl ass pl at es + 1 gask et , for 1 mm gel

1 mm Gaskets 3/pk, RM

2398237 5unit
EUR 257

Recombinant Human IGF-II Protein

PROTP01344-1 50ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.

Recombinant Murine IGF-I Protein

PROTP05017-1 50ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant murine IGF-I is a 7.6 kDa globular protein containing amino acids including 3 intra-molecular disulfide bonds.

Recombinant Human IGF-I Protein

PROTP05019-1 500ug
EUR 317
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.

Recombinant Human IGF-BP1 Protein

PROTP08833-1 25ug
EUR 317
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A).

Recombinant Human IGF-BP4 Protein

PROTP22692-1 20ug
EUR 317
Description: IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway. The biological effects of IGF-BP4 can be regulated by Pregnancy Associated Plasma Protein A (PAPP-A), which reduces IGF-BP4/IGF binding affinity by proteolytically cleaving IGF-BP4. The modulation of IGF-BP4 activity by PAPP-A is an important component in the regulation of ovarian folliculogenesis and in the growth inhibition of responding ovarian cancer cells. Recombinant human IGF-BP4 is a 25.8 kDa protein consisting of 237 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Recombinant Human IGF-BP5 Protein

PROTP24593-1 25ug
EUR 317
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.

Human Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EI1001-1 96 Well Plate
EUR 477

Mouse Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EMI1001-1 96 Well Plate
EUR 477

Clips 4/pk RM

2398239 6unit
EUR 250

1mm Pressure Platen - RM

2398242 3unit
EUR 281

Anti-IGF-1R (Ab-1161) Antibody

A00070-1 100ul
EUR 397
Description: Rabbit Polyclonal IGF-1R (Ab-1161) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

IGF-1, human

RC216-12 1mg
EUR 376.25

IGF-1, rat

RC256-12 50ug
EUR 152.66

IGF-1, Human

HY-P7018 10ug
EUR 108

IGF-1, Mouse

HY-P7070 100ug
EUR 452

LR3-IGF-1

E21-032 10ug
EUR 343

IGF-1-Fc

E13-m003-2 50μg
EUR 830

IGF-1 Protein

abx060289-100ug 100 ug
EUR 411

IGF- 1 Antibody

ABD6096 100 ug
EUR 438

IGF-1 Antibody

DF6096 200ul
EUR 304
Description: IGF-1 Antibody detects endogenous levels of total IGF-1.

rHu IGF-1

AK8530-0020 20µg Ask for price

rHu IGF-1

AK8530-0100 100µg Ask for price

rHu IGF-1

AK8530-1000 1mg Ask for price

IGF- 1 Plasmid

PVT7112 2 ug
EUR 266

0.75mm Plate Set,RM-075

2393014 2unit
EUR 263
Description: 1 pai r of gl ass pl at es + 1 gask et , for 0.75 mm gel

5 mm Dummy Plate, RM

2393074 10unit
EUR 241
Description: Pl ast i c pl at e for r unni ng 1 Pagel pr ecast gel onl y

2mm Plate Set,RM-22

2393740 3unit
EUR 281
Description: 1 pai r of gl ass pl at es + 1 gask et , for 2 mm gel

7 mm Dummy Plate, RM

2398247 10unit
EUR 241
Description: Pl ast i c pl at e for r unni ng 1 hand-cast gel onl y

1 mm 21-well Combs 2/pk, RM

2398255 5unit
EUR 272

IGF-1 ELISA Kit

DEIA1901 96T
EUR 757
Description: The IGF-1 ELISA is an enzyme immunoassay for the quantitative in vitro diagnostic measurement of Insulin-like Growth Factor 1 (IGF-1) in serum.

Mouse IGF-1 Antibody

33079-05111 150 ug
EUR 261

IGF-I (1-3)

5-01367 4 x 5mg Ask for price

IGF-1(M23) Antibody

BNC040220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF405S conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC040220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF405S conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC470220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF647 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC470220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF647 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC550220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF555 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC550220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF555 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCB0220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), Biotin conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCB0220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), Biotin conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC810220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF680R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC810220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF680R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC700220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF770 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC700220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF770 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC880220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF488A conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC880220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF488A conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC940220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF594 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC940220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF594 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC680220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF568 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC680220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF568 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCA0220-250 250uL
EUR 383
Description: Primary antibody against IGF-1(M23), APC conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCAP0220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCAP0220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNUM0220-50 50uL
EUR 395
Description: Primary antibody against IGF-1(M23), 1mg/mL

IGF-1(M23) Antibody

BNCP0220-250 250uL
EUR 383
Description: Primary antibody against IGF-1(M23), PerCP conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC050220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF405M conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC050220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF405M conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC400220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF640R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC400220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF640R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCR0220-250 250uL
EUR 383
Description: Primary antibody against IGF-1(M23), RPE conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNUB0220-100 100uL
EUR 209
Description: Primary antibody against IGF-1(M23), Concentration: 0.2mg/mL

IGF-1(M23) Antibody

BNUB0220-500 500uL
EUR 458
Description: Primary antibody against IGF-1(M23), Concentration: 0.2mg/mL

IGF-1(M23) Antibody

BNC430220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF543 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC430220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF543 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCH0220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNCH0220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC610220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF660R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC610220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF660R conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC800220-100 100uL
EUR 199
Description: Primary antibody against IGF-1(M23), CF680 conjugate, Concentration: 0.1mg/mL

IGF-1(M23) Antibody

BNC800220-500 500uL
EUR 544
Description: Primary antibody against IGF-1(M23), CF680 conjugate, Concentration: 0.1mg/mL

Human IGF-1 LR3

SP-89927-100 100 ug
EUR 225

IGF-1, human recombinant

P1016-.02 20 µg
EUR 258
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

IGF-I (1-3)

H-2468.0250 250.0mg
EUR 176
Description: Sum Formula: C12H19N3O6; CAS# [32302-76-4]

IGF-I (1-3)

H-2468.1000 1.0g
EUR 466
Description: Sum Formula: C12H19N3O6; CAS# [32302-76-4]

IGF-1 Blocking Peptide

DF6096-BP 1mg
EUR 195

rHu IGF-1 (cGMP)

AK9901-0000 1mg Ask for price

A-M310 agarGEL RM, 10/pk

2332200 2unit
EUR 351
Description: pH 3 - 10

A-M38 agarGEL RM, 10/pk

2332210 2unit
EUR 351
Description: pH 3 - 8

A-M58 agarGEL RM, 10/pk

2332220 2unit
EUR 351
Description: pH 5 - 8

A-M510 agarGEL RM, 10/pk

2332230 2unit
EUR 351
Description: pH 5 - 10

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